Cholera Cases Decrease 27%, But Vaccine Production Ramps Up

The World Health Organization (WHO) today announced two very positive trends related to the 7th cholera global outbreak.

On February 20, 2025, the WHO confirmed a 27% decrease in cholera cases since December 2024. A total of 34,799 new cholera and/or Acute Watery Diarrhoea cases were reported from 19 countries, territories, and areas across three WHO regions.

The period also saw a 33% decrease in related fatalities from the previous month.

This decrease was recorded despite a new cholera outbreak in Angola.

Additionally, the WHO reported that in January 2025, Oral Cholera Vaccine (OCV) production reached 6.2 million doses, a recent high point compared to December 2024, when 5.5 million doses were produced.

This progress follows introducing and prequalifying a new vaccine formulation and manufacturing process earlier in 2024.

However, the current OCV production has yet to meet growing global demand, and demand continues to exceed supply, says the WHO.

In the United States, OCVs will be offered at travel clinics and pharmacies in 2025.