Over 1 Million Dengue Cases Confirmed in Brazil in 2025

The Ministry of Health for the Federative Republic of Brazil recently confirmed a total of 1,019,033 dengue cases and 681 related fatalities this year.

As of April 12, 2025, São Paulo had reported the most dengue cases, at 590,850.

As of April 22, 2025, the U.S. Centers for Disease Control and Prevention (CDC) has identified more cases of dengue (1,481) than expected among U.S. travelers returning from countries with dengue outbreaks. 

In 2025, 54 travel-associated and one locally acquired dengue cases were reported in Florida.

Of dengue's four types, DENV-3 is the most common serotype identified, accounting for 84%.

To alert travelers to Brazil and other areas, the CDC reissued a Global Travel Health Notice on April 15, 2025, regarding Dengue outbreaks in the Americas. Additionally, the CDC encourages healthcare providers to increase testing of patients with symptoms related to dengue. 

Currently, dengue vaccines are unavailable in the U.S.