Sudan Ebolavirus Outbreak Quickly Ends

The Republic of Uganda today announced the end of the current Sudan Ebolavirus disease (SVD) outbreak, less than three months after the virus was confirmed in the capital Kampala. 

This strain of Ebolaviris often causes a severe, fatal illness in infected people.

As of April 26, 2025, during this outbreak, 14 SVD cases, including 12 confirmed and two probable cases, had been reported.

And four deaths, two confirmed and two probable, occurred.

"This outbreak challenged us in new ways. It touched both urban and rural communities across the country and unfolded against the backdrop of significant global funding constraints," said Dr Chikwe Ihekweazu, Acting WHO Regional Director for Africa, in a press release on April 26, 2025.

"The response demonstrated Uganda's long-standing leadership in tackling public health emergencies. As WHO, we are extremely proud to have supported these efforts every step of the way."

Despite the absence of licensed countermeasures against this species of Ebolavirus, Sudan candidate vaccines are in various phases of clinical trials. Within four days of the government's declaration of the outbreak, a randomized clinical trial for vaccine safety and efficacy using the ring vaccination approach was launched.

In addition, the administration of Remdesivir treatment under the Monitored Emergency Use of Unregistered and Experimental Interventions protocol was initiated.

As of today, various Sudan vaccine candidates are being tested in clinical research,

Previously, Zaire Ebolavirus vaccines and therapeutics had been approved for use in Africa,

In addition to Eboa, Uganda is experiencing polio and mpox outbreaks in 2026. Vaccines for these diseases are commercially available in the U.S.