Mpox 1b Cases Confirmed in 20 Countries

According to the World Health Organization (WHO), the clade Ib monkeypox virus (MPXV) outbreak began in September 2023 and continues predominantly in the Democratic Republic of the Congo, Burundi, and Uganda, with travel-related cases identified in other countries.

In Africa, from January 2024 to January 5, 2025, 14,700 confirmed mpox cases, including 66 deaths (CFR – 0.4%), have been reported by 20 countries. And continues to meet the WHO criteria for a public health emergency of international concern.

As of January 14, 2025, the ECDC reported eleven individuals with MPXV clade I in the EU/EEA since August 2024.

One case was reported by Sweden in August 2024, seven by Germany (one in October, five in December 2024, and one in January 2025), two cases by Belgium in December 2024, and one case by France in January 2025

The WHO says two virus types cause mpox, clade I and II. Both types spread the same way and can be prevented using the same methods, including vaccination.

Most mpox outbreaks in other areas are due to clade IIb MPXV, a continuation of the multi-country outbreak that began in May 2022.

In the United States, the CDC assessed on January 10, 2025, the overall risk to the population(s) posed by the clade I mpox outbreak as low. And clade II mpox is still circulating at low levels.

Various mpox vaccines continue to be available in impacted countries.

Note: Updated on Jan. 14, 2025, to include ECDC data.